Antifungal Activity Of The Ethanolic Extract Of White Chrysanthemum Leaves (Chrysanthemum Morifolium (Ramat.) Hemsl. Against Candida Albicans And Pityrosporum Ovale

Penulis

  • Jane Melita Keliat University of Sumatera Utara, Medan, Indonesia
  • Nabilla Azzahra University of Sumatera Utara, Medan, Indonesia
  • Dwi Lestari P University of Sumatera Utara, Medan, Indonesia
  • Sonia Meliana Aritonang University of Sumatera Utara, Medan, Indonesia

DOI:

https://doi.org/10.55129/jnerscommunity.v13i2.2813

Abstrak

White chrysanthemum (Chrysanthemum morifolium (Ramat.) Hemsl.) is an ornamental plant cultivated in Raya Village, Berastagi, North Sumatera which has potential as an antifungal. In this study, the antifungal activity test used agar diffusion method with paper disc as media in various concentrations, namely 500; 250; 50;10; 5; 2.5; 1.25; 0.625 mg/ml with  positive control of ketoconazole and negative control of DMSO. Minimum Inhibitory Concentration (MIC) of ethanol extract of white chrysanthemum leaves against Candida albicans and Pityrosporum ovale at a concentration of 10 mg/ml with inhibition zone diameters of 6.83 mm and 7.76 mm

Referensi

Alviana,N.2016.AntibacterialEffectiveness Test of Chrysanthemum Leaf Ethanol Extract (Chrysanthemum morifolium grandiflora) Against Staphylococcus aureus and Escherichia coli. Thesis Journal.

Azhar, MA, Mulqie, L., and Hazar, S. 2020. The Potential of Several Types of Herbs Has Antifungal Activity Against Candida Albicans. Pharmacy Proceedings. 6(2): 656.

Davis, W.W. and TR Stout. 1971. Disc plate methods of microbiological antibiotic assay. Microbiology : 659. .

Faturrahman, Sukiman, Suryadi, BF, Sarkono, and Hidayati, E. 2021. Comparison Antimicrobial Activity of Ethanol Extract from Three Ganoderma Species from Lombok Island. Journal of Science Technology & Environment. 7(2) : 168.

Ganiswarna, SG 2016. Pharmacology And Therapy 6th Edition. In the Department of Pharmacology and FKUI Therapeutics.

Hidana, R. and Fauziyyah, DK 2016. Inhibitory Power of Soursop Leaf Infusion (Annona muricata L.) Against Fungal Growth Pityrosporum ovale. Bakti Tunas Husada Health Journal: Journal of Nursing Sciences, Health Analyst and Pharmacy. 15(1):100-108.

Lutfiyanti, R., Ma'ruf, WF, and Dewi, EN 2012. Antifungal Activity of Bioactive Compounds Extract Gelidium latifolium to Candida albicans. J processing and biotechnology of fishery products. Volume 1 Number 1. Pg:26-33.

Marantika, VM and Trimulyono, G. 2019. Antifungal Activity of Extracts Lichen Parmelia sulcataon Fungal Growth Alternaria Porri. Bio Lantern Vol. 8(3):231,236.

Octaviani, M., Fadhli, H., and Yuneistya, E. 2019. Antimicrobial Activity Test of Ethanol Extract of Shallot Skin (Allium is fast L.) with the Disc Diffusion Method. Pharmaceutical Sciences and Research. 6(1):66.

Sassi, AB, Skhiri, FH, Bourgougnon, N., and Aouni, M. 2008. Antimicrobial activities of four Tunisian Chrysanthemum species.Indian J Med Res. 127(1): 187.

Setiawan, A., Setiawan, F., Juliasih, NLGR, Widyastuti, W., Laila, A., Setiawan, WA, et al. 2022. Fungicide Activity of Culture Extract from Kocuria palustris 19C38A1 against Fusarium oxysporum. Journal of fungi. 8(3):280.

Ukiya M., Akihisa, T., Tokuda, H., Suzuki, H., Mukainaka, T., Ichiisi, E.,et al. 2002. Antitumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers. Cancer Letters. 177(1): 7-12.

Utami, AR, Sukohar, A., Setiawan, G., and Morfi, CW 2018. Effects of Using Pomade Against Dandruff Incidence in Adolescent Boys majority. 7(2): 189. Utami, YP,

Yulianti, D., Sunyoto, M., and Wulandari, E. 2019. Antioxidant Activity of Centella asiatica Leaves (Centella asiatica L.Urban) and Chrysanthemum (Chrysanthemum Sp) At Three Variations Of Drying Temperature. Pasundan Food Technology Journal. 6(3): 143.

Unduhan

Diterbitkan

11-04-2023

Cara Mengutip

Melita Keliat, J., Azzahra, N. ., Lestari P, D. ., & Meliana Aritonang, S. (2023). Antifungal Activity Of The Ethanolic Extract Of White Chrysanthemum Leaves (Chrysanthemum Morifolium (Ramat.) Hemsl. Against Candida Albicans And Pityrosporum Ovale. Journals of Ners Community, 14(2), 452–456. https://doi.org/10.55129/jnerscommunity.v13i2.2813